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This testing is added based on the criteria described above in When to test. In people without Down syndrome, studies have demonstrated that red blood cell folate and serum folate testing provide equivalent data

The study concluded that serum cobalamin levels should be monitored as some dogs may need long-term supplementation

So whats the thinking behind replacing the time-honoured treatment of PA by injections with tablets

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Functions as a for metabolic reaction required for synthesis of purines and pyrimidines: co-enzyme The reaction depends on methyl cobalamin as a co-factor and is also dependent on folate, in which the methyl group of methyltetrahydrofolate is transferred to homocysteine to form methionine and tetrahydrofolate